Name : Human Betacellulin Protein
Product Source :
Recombinant Human Betacellulin Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Asp32-Gln118.[Accession | P35070]
Molecular Weight :
The protein has a predicted MW of 36.52 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human Betacellulin on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human Betacellulin is greater than 95% as determined by SEC-HPLC.
Background :
Betacellulin (BTC) belongs to the epidermal growth factor (EGF) family of peptide ligands that are characterised by a six-cysteine consensus motif that forms three intra-molecular disulfide bonds crucial for binding the ErbB receptor family.
Synonyms :
ProBetacellulin; BTC
References & Citations :
Dunbar AJ, Goddard C. Structure-function and biological role of Betacellulin. Int J Biochem Cell Biol. 2000 Aug;32(8):805-15. doi: 10.1016/s1357-2725(00)00028-5. PMID: 10940639.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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