Name : Biotinylated Human BTN2A1 Protein

Product Source :
Recombinant Biotinylated Human BTN2A1 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. It contains Gln29-Ala248.[Accession | Q7KYR7-1]

Molecular Weight :
The protein has a predicted MW of 27.47 kDa. Due to glycosylation, the protein migrates to 43-55 kDa based on Tris-Bis PAGE result.

Endotoxin Level :
Less than 1EU per μg by the LAL method.

Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC

Formulation :
Supplied as 0.22 μm filtered solution in PBS (pH 7.4).

Reconstitution :

Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Product Concentration :
Tris-Bis PAGE Biotinylated Human BTN2A1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Biotinylated Human BTN2A1 is greater than 95% as determined by SEC-HPLC.

Background :
The MHC-encoded butyrophilin, BTN2A1, is a cell surface glycoprotein related to the extended family of B7 costimulatory molecules. BTN2A1 mRNA was expressed in most human tissues, but protein expression was significantly lower in leukocytes.

Synonyms :
BT2.1; BTF1; BK14H9.1; BTF1BT2.1; DJ3E1.1; FLJ36567

References & Citations :
Malcherek G, Mayr L, Roda-Navarro P, Rhodes D, Miller N, Trowsdale J. The B7 homolog butyrophilin BTN2A1 is a novel ligand for DC-SIGN. J Immunol. 2007 Sep 15;179(6):3804-11. doi: 10.4049/jimmunol.179.6.3804. PMID: 17785817.

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