Name : Human BTN2A1 Protein
Product Source :
Recombinant Human BTN2A1 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Gln29-Ala248.[Accession | Q7KYR7-1]
Molecular Weight :
The protein has a predicted MW of 25.65 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human BTN2A1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human BTN2A1 is greater than 95% as determined by SEC-HPLC. SPR Data Human BTN2A1, His Tag immobilized on CM5 Chip can bind Human CD209, His Tag with an affinity constant of 0.12 μM as determined in SPR assay (Biacore T200).
Background :
The MHC-encoded butyrophilin, BTN2A1, is a cell surface glycoprotein related to the extended family of B7 costimulatory molecules. BTN2A1 mRNA was expressed in most human tissues, but protein expression was significantly lower in leukocytes.
Synonyms :
BT2.1; BTF1; BK14H9.1; BTF1BT2.1; DJ3E1.1; FLJ36567
References & Citations :
Malcherek G, Mayr L, Roda-Navarro P, Rhodes D, Miller N, Trowsdale J. The B7 homolog butyrophilin BTN2A1 is a novel ligand for DC-SIGN. J Immunol. 2007 Sep 15;179(6):3804-11. doi: 10.4049/jimmunol.179.6.3804. PMID: 17785817.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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