Name : Human CKAP4 Protein

Product Source :
Recombinant Human CKAP4 Protein is expressed from E.coli with His tag at the N-Terminus. It contains His128-Val602.[Accession | Q07065]

Molecular Weight :
The protein has a predicted MW of 53.66 kDa same as Tris-Bis PAGE result.

Endotoxin Level :
Less than 1EU per μg by the LAL method.

Purity :
> 90% as determined by Tris-Bis PAGE> 90% as determined by HPLC

Formulation :
Supplied as 0.22μm filtered solution in PBS, 200mM NaCl, 10% Glycerol (pH 7.4).

Reconstitution :

Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Product Concentration :
Tris-Bis PAGE Human CKAP4 on Tris-Bis PAGE under reduced condition. The purity is greater than 90%. SEC-HPLC The purity of Human CKAP4 Protein is greater than 90% as determined by SEC-HPLC.

Background :
Cytoskeleton-associated protein 4 (CKAP4) is located in the rough endoplasmic reticulum (ER) and plays an important role in stabilizing the structure of ER. Meanwhile, CKAP4 is also found to act as an activated receptor at the cell surface.

Synonyms :
Climp-63; p63;CLIMP-63; ERGIC-63;

References & Citations :
Li SX, Li J, Dong LW, Guo ZY. Cytoskeleton-Associated Protein 4, a Promising Biomarker for Tumor Diagnosis and Therapy. Front Mol Biosci. 2021 Feb 5;7:552056. doi: 10.3389/fmolb.2020.552056. PMID: 33614703; PMCID: PMC7892448.

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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