Name : Human CD24 Protein-VLP
Product Source :
Recombinant Human CD24 Protein-VLP is expressed from HEK293. It contains Ser27-Gly59.[Accession | P25063-1]
Molecular Weight :
The target protein has a predicted MW of 5.0 kDa.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
Formulation :
Supplied as 0.22μm filtered solution in PBS (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
ELISA Data Immobilized Human CD24 VLP at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-CD24 Antibody, hFc Tag with the EC50 of 16.4ng/ml determined by ELISA.
Background :
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers.
Synonyms :
CD 24; CD24 molecule; CD24A; FLJ22950; FLJ43543; MGC75043
References & Citations :
(1)Barkal AA, et al.CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy.Nature. 2019 Jul 31. doi: 10.1038/s41586-019-1456-0.D
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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