Name : Human AGR-2 Protein
Product Source :
Recombinant Human AGR-2 Protein is expressed from E.coli with His tag at the C-Terminus. It contains Arg21-Leu175.[Accession | NP_006399.1]
Molecular Weight :
The protein has a predicted MW of 18.77 kDa same as Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Supplied as 0.22μm filtered solution in 50mM Tris, 300mM NaCl, 1mM TCEP (pH 7.5).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human AGR-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human AGR-2 is greater than 95% as determined by SEC-HPLC. SPR Data Human EpCAM, hFc Tag captured on CM5 Chip via Protein A can bind Human AGR-2, His Tag with an affinity constant of 6.91 μM as determined in SPR assay (Biacore T200).
Background :
Anterior gradient homolog 2 (AGR2) is a functional protein with critical roles in a diverse range of biological systems, including vertebrate tissue development, inflammatory tissue injury responses, and cancer progression.
Synonyms :
Anterior gradient protein 2 homolog; AG-2; AG2; hAG-2; hAG 2; HPC8; AGR2
References & Citations :
Wu J, Wang C, Li X, Song Y, Wang W, Li C, Hu J, Zhu Z, Li J, Zhang W, Lu Z, Yang CJ. Identification, characterization and application of a G-quadruplex structured DNA aptamer against cancer biomarker protein anterior gradient homolog 2. PLoS One. 2012;7(9):e46393. doi: 10.1371/journal.pone.0046393. Epub 2012 Sep 28. PMID: 23029506; PMCID: PMC3460915.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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