Name : Mouse CD21 Protein
Product Source :
Recombinant Mouse CD21 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ile12-Trp963.[Accession | P19070]
Molecular Weight :
The protein has a predicted MW of 106.03 kDa. Due to glycosylation, the protein migrates to 130-160 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 90% as determined by Tris-Bis PAGE
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse CD21 on Tris-Bis PAGE under reduced condition. The purity is greater than 90%.
Background :
A natural soluble form of CD21 that is cleaved from lymphocyte membrane CD21 circulates in normal human serum. Soluble CD21 retains the capacity to bind iC3b and CD23, the known ligands of membrane CD21. In a similar fashion to IgE complexes, another ligand of CD23, the soluble CD21 was shown to efficiently trigger CD23-signalling pathways in human monocytes.
Synonyms :
EBV receptor; CD21; C3DR; CR2; C3DRSLEB9; CVID7; SLEB9
References & Citations :
(1)Frémeaux-Bacchi V, Kolb JP, Rakotobé S, Kazatchkine MD, Fischer EM. Functional properties of soluble CD21. Immunopharmacology. 1999 May;42(1-3):31-7. doi: 10.1016/s0162-3109(99)00026-0. PMID: 10408363.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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