Name : Human CD69/CLEC2C Protein
Product Source :
Recombinant Human CD69/CLEC2C Protein is expressed from HEK293 with His tag at the N-Terminus. It contains Ser62-Lys199.[Accession | Q07108]
Molecular Weight :
The protein has a predicted MW of 17.07kDa. Due to glycosylation, the protein migrates to 24-27kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human CD69 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human CD69 is greater than 95% as determined by SEC-HPLC.
Background :
CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. CLEC2C is a disulfide-linked homodimer protein with two differentially glycosylated subunits.
Synonyms :
CD69; CLEC2C; EA1; BL-AC/P26; AIM; BL-AC; P26; GP32; 28; MLR-3
References & Citations :
(1) Ziegler SF, Ramsdell F, Alderson MR. The activation antigen CD69. Stem Cells. 1994 Sep;12(5):456-65. doi: 10.1002/stem.5530120502. PMID: 7804122.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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