Name : Biotinylated Human CD94 Protein
Product Source :
Recombinant Biotinylated Human CD94 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus. It contains Ser34-Ile179.[Accession | Q13241-1]
Molecular Weight :
The protein has a predicted MW of 19.8 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Biotinylated Human CD94 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%. SEC-HPLC The purity of Biotinylated Human CD94 is greater than 95% as determined by SEC-HPLC.
Background :
CD94 is an approximately 25 kDa type 2 transmembrane protein that plays an important role in regulating natural killer (NK) cell activation.CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Synonyms :
CD94; KLRD1; KP43; NK cell receptor
References & Citations :
(1)Walsh C E , Ryan E J , Cliona O’Farrelly, et al. Differential Expression of NK Receptors CD94 and NKG2A by T Cells in Rheumatoid Arthritis Patients in Remission Compared to Active Disease[J]. PLOS ONE, 2011, 6.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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