Name : Cynomolgus DDT Protein
Product Source :
Recombinant Cynomolgus DDT Protein is expressed from E.coli with His tag at the N-Terminus. It contains Pro2-Leu118.[Accession | XP_005595435.2]
Molecular Weight :
The protein has a predicted MW of 13.37 kDa same as Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Supplied as 0.22μm filtered solution in 50mM Tris, 150mM NaCl, 10% Glycerol (pH 8.0).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Cynomolgus DDT on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum at similar concentrations as MIF. D-DT binds the MIF cell surface receptor complex, CD74/CD44, with high affinity and induces similar cell signaling and effector functions.
Synonyms :
D-DT; D-dopachrome decarboxylase; D-dopachrome tautomerase; Phenylpyruvate tautomerase II; EC 4.1.1.84; MIF2; DDCT
References & Citations :
Merk M, Mitchell RA, Endres S, Bucala R. D-dopachrome tautomerase (D-DT or MIF-2): doubling the MIF cytokine family. Cytokine. 2012 Jul;59(1):10-7. doi: 10.1016/j.cyto.2012.03.014. Epub 2012 Apr 14. PMID: 22507380; PMCID: PMC3367028.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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