Name : Mouse EMAP-II/AIMP1 Protein
Product Source :
Recombinant Mouse EMAP-II/AIMP1 Protein is expressed from E.coli with His tag at the N-Terminus. It contains Ala2-Lys310.[Accession | P31230]
Molecular Weight :
The protein has a predicted MW of 35.1 kDa. The protein migrates to 42-46 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Supplied as 0.22μm filtered solution in 20mM Tris, 500mM NaCl, 10% Glycerol (pH 8.0).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse EMAP-II/AIMP1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
The potent antiangiogenic and proinflammatory protein Endothelial Monocyte Activating Polypeptide II (EMAP II) has been described as a mediator of pulmonary vascular and alveolar formation and its expression is inversely related to the periods of vascularization and alveolarization in the developing lung. Hence the study of EMAP II could play a vital role in studying and devising appropriate therapeutics for diseases of aberrant lung development, such as BPD.
Synonyms :
EMAP-2; EMAP-II; AIMP1; HLD3; SCYE1; p43
References & Citations :
(1) Lal CV, Schwarz MA. Vascular mediators in chronic lung disease of infancy: role of endothelial monocyte activating polypeptide II (EMAP II). Birth Defects Res A Clin Mol Teratol. 2014 Mar;100(3):180-8. doi: 10.1002/bdra.23234. Epub 2014 Mar 12. PMID: 24619875; PMCID: PMC4280095.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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