Product Name :
Bexagliflozin
Description:
Bexagliflozin (EGT1442) is a potent, selective and orally active sodium glucose co-transporter 2 (SGLT2) inhibitor, with IC50s of 2 nM and 5.6 μM for human SGLT2 and SGLT1, respectively. Bexagliflozin can be used for the research of type 2 diabetics.
CAS:
1118567-05-7
Molecular Weight:
464.94
Formula:
C24H29ClO7
Chemical Name:
(2S,3R,4R,5S,6R)-2-(4-chloro-3-[4-(2-cyclopropoxyethoxy)phenyl]methylphenyl)-6-(hydroxymethyl)oxane-3,4,5-triol
Smiles :
OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)C1C=CC(Cl)=C(CC2C=CC(=CC=2)OCCOC2CC2)C=1
InChiKey:
BTCRKOKVYTVOLU-SJSRKZJXSA-N
InChi :
InChI=1S/C24H29ClO7/c25-19-8-3-15(24-23(29)22(28)21(27)20(13-26)32-24)12-16(19)11-14-1-4-17(5-2-14)30-9-10-31-18-6-7-18/h1-5,8,12,18,20-24,26-29H,6-7,9-11,13H2/t20-,21-,22+,23-,24+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Bexagliflozin (EGT1442) is a potent, selective and orally active sodium glucose co-transporter 2 (SGLT2) inhibitor, with IC50s of 2 nM and 5.6 μM for human SGLT2 and SGLT1, respectively. Bexagliflozin can be used for the research of type 2 diabetics.|Product information|CAS Number: 1118567-05-7|Molecular Weight: 464.94|Formula: C24H29ClO7|Chemical Name: (2S,3R,4R,5S,6R)-2-(4-chloro-3-[4-(2-cyclopropoxyethoxy)phenyl]methylphenyl)-6-(hydroxymethyl)oxane-3,4,5-triol|Smiles: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)C1C=CC(Cl)=C(CC2C=CC(=CC=2)OCCOC2CC2)C=1|InChiKey: BTCRKOKVYTVOLU-SJSRKZJXSA-N|InChi: InChI=1S/C24H29ClO7/c25-19-8-3-15(24-23(29)22(28)21(27)20(13-26)32-24)12-16(19)11-14-1-4-17(5-2-14)30-9-10-31-18-6-7-18/h1-5,8,12,18,20-24,26-29H,6-7,9-11,13H2/t20-,21-,22+,23-,24+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 100 mg/mL (215.Toceranib Autophagy 08 mM).Rivastigmine Cholinesterase (ChE) |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:33103468 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Bexagliflozin (0.1-10 mg/kg; p.o.) lowers blood glucose levels in a dose-dependent manner after glucose challenge (20%; 2 g/kg; p.o.).|Products are for research use only. Not for human use.|