Name : Human GPC3 Protein-VLP
Product Source :
Recombinant Human GPC3 Protein-VLP is expressed from E.coli. It contains Gly510-Asn554.[Accession | P51654-1]
Molecular Weight :
The target protein has a predicted MW of 14 kDa.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
Formulation :
Supplied as 0.22μm filtered solution in 20mM HEPES, 500mM NaCl, 10% Glycerol, 0.1% Tween20 (pH 7.7).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
ELISA Data Immobilized Human GPC3 VLP at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-GPC3 Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA.
Background :
Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several therapeutic anti-GPC3 antibodies have been developed.
Synonyms :
GPC3; DGSX; Glypican 3; GTR2-2; MXR7; OCI5; OCI-5; SGB; SGBS; SGBS1SDYS; SDYS; SGBS1
References & Citations :
(1)Ho M , Kim H. Glypican-3: A new target for cancer immunotherapy[J]. European Journal of Cancer, 2011, 47(3):0-338.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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