Name : Mouse IL-17B Protein
Product Source :
Recombinant Mouse IL-17B Protein is expressed from E.coli with His tag at the N-Terminus. It contains His21-Phe180.[Accession | Q9QXT6]
Molecular Weight :
The protein has a predicted MW of 19.1 kDa same as Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Lyophilized from 0.22μm filtered solution in 20mM PB, 2mM DTT, 300mM NaCl, 200mM Arginine (pH 7.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse IL-17B on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. IL-17B/IL-17RB expression patterns and biological activities in cancer and highlight issues that remain to be addressed to better characterize IL-17B and its receptor as potential targets for enhancing the effectiveness of the existing cancer therapies.
Synonyms :
IL-17B; Cytokine CX1; IL20; interleukin 17B; interleukin 20; MGC138900; MGC138901; NIRF; ZCYTO7
References & Citations :
(1) Bastid J, Dejou C, Docquier A, Bonnefoy N. The Emerging Role of the IL-17B/IL-17RB Pathway in Cancer. Front Immunol. 2020 Apr 21;11:718. doi: 10.3389/fimmu.2020.00718. PMID: 32373132; PMCID: PMC7186465.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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