Name : Cynomolgus IL-9 Protein
Product Source :
Recombinant Cynomolgus IL-9 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Arg19-Ile144.[Accession | A0A7N9IA33 ]
Molecular Weight :
The protein has a predicted MW of 14.01 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Cynomolgus IL-9 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma.
Synonyms :
Interleukin-9; IL-9; Cytokine P40; T-cell growth factor P40; HP40; P40
References & Citations :
(1) Koch S, Sopel N, Finotto S. Th9 and other IL-9-producing cells in allergic asthma. Semin Immunopathol. 2017 Jan;39(1):55-68. doi: 10.1007/s00281-016-0601-1. Epub 2016 Nov 17. PMID: 27858144.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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