Name : Human IL-19 Protein
Product Source :
Recombinant Human IL-19 Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Leu25-Ala177.[Accession | Q9UHD0-1]
Molecular Weight :
The protein has a predicted MW of 44.6 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Supplied as 0.22μm filtered solution in 20mM Tris, 500mM NaCl (pH 8.0).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human IL-19 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human IL-19 is greater than 95% as determined by SEC-HPLC.
Background :
Interleukin-19 (IL-19) has been shown to be involved in coronary artery diseases and atherosclerosis, while its expression in myocardial infarction is poorly understood. In this study, the dynamic increase in circulating IL-19 in acute ST-segment elevation myocardial infarction (STEMI) patients was detected.IL-19 is correlated with the severity of acute myocardial infarction, which may be a new idea for the clinical treatment of myocardial infarction.
References & Citations :
(1) Qi L, Zhang J, Wu K, Shi S, Ji Q, Miao H, Que B. IL-19 as a Biomarker for the Severity of Acute Myocardial Infarction. Arch Med Res. 2020 Feb;51(2):160-166. doi: 10.1016/j.arcmed.2020.01.007. Epub 2020 Feb 26. PMID: 32111500.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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