Product Name: PF-543
Subtitle: SphK1 inhibitor,cell-permeate,potent and selective
Biological Activity: Biological Activity of PF-543Description PF-543 is a novel cell-permeable inhibitor of SphK1 with Ki value of 3.6 nM. Targets SphK1 IC50 3.6 nM (Ki)
SMLES: CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCCC3CO)CS(=O)(=O)C4=CC=CC=C4
CAS NO: 34233-69-7
Standard In CHIKey: AChE inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C27H31NO4S
M.Wt: 465.6
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/2/450
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: [(2R)-1-[[4-[[3-(benzenesulfonylmethyl)-5-methylphenoxy]methyl]phenyl]methyl]pyrrolidin-2-yl]methanol