Product Name: Zileuton
Subtitle: 5-lipoxygenase (5-LOX) inhibitor, orally active
Biological Activity: Biological Activity of ZileutonOrally active 5-lipoxygenase (5-LOX) inhibitor that inhibits LTB4 synthesis (IC50 values are 0.56, 2.3 and 2.6 μM in dog, rat and human blood respectively). Inhibits antigen-induced contraction of tracheal strips in vit
SMLES: CC(C1=CC2=CC=CC=C2S1)N(C(=O)N)O
CAS NO: 1092939-17-7
Standard In CHIKey: MWLSOWXNZPKENC-UHFFFAOYSA-NProtein Tyrosine Kinase_RTK inhibitors
Standard InChI: InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)
Typrof Compound:
Appearance:
Formula: C11H12N2O2S
M.Wt: 236.29
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/2/612
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea