Name : Mouse MOG/Myelin Oligodendrocyte Glycoprotein Protein
Product Source :
Recombinant Mouse MOG/Myelin Oligodendrocyte Glycoprotein Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Gly29-Thr156.[Accession | Q61885]
Molecular Weight :
The protein has a predicted MW of 15.68 kDa. Due to glycosylation, the protein migrates to 18-25 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse MOG on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
Myelin oligodendrocyte glycoprotein (MOG) antibody disease is a rare autoimmune disorder with antibodies against the MOG predominantly involving the optic nerve and spinal cord leading to vision loss and paralysis. When MOG antibody disease involves the brain, the phenotype is similar to acute disseminated encephalomyelitis (ADEM).
Synonyms :
MOG; MGC26137; MOG Ig-AluB; MOGIG2; BTN6; BTNL11; NRCLP7
References & Citations :
(1) Salama S, Khan M, Pardo S, Izbudak I, Levy M. MOG antibody-associated encephalomyelitis/encephalitis. Mult Scler. 2019 Oct;25(11):1427-1433. doi: 10.1177/1352458519837705. Epub 2019 Mar 25. PMID: 30907249; PMCID: PMC6751007.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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