Name : Human MXRA8 Protein
Product Source :
Recombinant Human MXRA8 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Val20-Gln341.[Accession | Q9BRK3-1]
Molecular Weight :
The protein has a predicted MW of 36.70 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human MXRA8 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human MXRA8 is greater than 95% as determined by SEC-HPLC.
Background :
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O’nyong nyong (ONNV) viruses.
Synonyms :
Adipocyte-specific protein 3; Adipocyte-specific 3; DICAM; Asp3; Limitrin
References & Citations :
Zhang R, Earnest JT, Kim AS, Winkler ES, Desai P, Adams LJ, Hu G, Bullock C, Gold B, Cherry S, Diamond MS. Expression of the Mxra8 Receptor Promotes Alphavirus Infection and Pathogenesis in Mice and Drosophila. Cell Rep. 2019 Sep 3;28(10):2647-2658.e5. doi: 10.1016/j.celrep.2019.07.105. PMID: 31484075; PMCID: PMC6745702.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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