Name : Biotinylated Mouse uPAR/PLAUR Domain (2+3) Protein
Product Source :
Recombinant Biotinylated Mouse uPAR/PLAUR Domain (2+3) Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. It contains Leu117-Gly298.[Accession | P35456-1]
Molecular Weight :
The protein has a predicted MW of 22.37 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Biotinylated Mouse uPAR Domain (2+3) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Biotinylated Mouse uPAR Domain (2+3) is greater than 95% as determined by SEC-HPLC.
Background :
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
Synonyms :
U-PAR; uPAR; CD87; PLAUR; MO3; UPAR
References & Citations :
(1) Blasi F. The urokinase receptor and cell migration. Semin Thromb Hemost. 1996;22(6):513-6. doi: 10.1055/s-2007-999053. PMID: 9122717.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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