Product Name: WP1066
Subtitle: JAK2/STAT3 inhibitor,cell-permeable
Biological Activity: Biological Activity of WP1066Description WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells. Targets JAK2 STAT3 IC50 2.3 μM 2.43 μM
SMLES: CC(C1=CC=CC=C1)NC(=O)C(=CC2=NC(=CC=C2)Br)C#N
CAS NO: 0
Standard In CHIKey: VD_VDR inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C17H14BrN3O
M.Wt: 356.22
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/3/781
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: (E)-3-(6-bromopyridin-2-yl)-2-cyano-N-[(1S)-1-phenylethyl]prop-2-enamide