Name : Human PTH Protein
Product Source :
Recombinant Human PTH Protein is expressed from HEK293 with hFc tag at the N-Terminus. It contains Ser32-Gln115.[Accession | P01270]
Molecular Weight :
The protein has a predicted MW of 34.95 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.4-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human PTH on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human PTH is greater than 95% as determined by SEC-HPLC.
Background :
Parathyroid hormone (PTH) is an 84-amino-acid peptide hormone that is secreted by the parathyroid gland. It has different administration modes in bone tissue through which it promotes bone formation (intermittent administration) and bone resorption (continuous administration) and has great potential for application in sbone defect repair.
Synonyms :
Parathyroid hormone; Parathormone; Parathyrin; PTH1
References & Citations :
Chen T, Wang Y, Hao Z, Hu Y, Li J. Parathyroid hormone and its related peptides in bone metabolism. Biochem Pharmacol. 2021 Oct;192:114669. doi: 10.1016/j.bcp.2021.114669. Epub 2021 Jul 2. PMID: 34224692.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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