Name : Human BPIFA1/LUNX Protein

Product Source :
Recombinant Human BPIFA1/LUNX Protein is expressed from E.coli without tag. It contains Gln20-Val256.[Accession | Q9NP55-1]

Molecular Weight :
The protein has a predicted MW of 24.8 kDa same as Tris-Bis PAGE result.

Endotoxin Level :
Less than 1EU per μg by the LAL method.

Purity :
> 95% as determined by Tris-Bis PAGE> 90% as determined by HPLC

Formulation :
Supplied as 0.22μm filtered solution in 50mM Tris, 150mM NaCl, 10% Glycerol (pH 8.5).

Reconstitution :

Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Product Concentration :
Tris-Bis PAGE Human BPIFA1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human BPIFA1 is greater than 90% as determined by SEC-HPLC.

Background :
Bactericidal/permeability-increasing fold containing family A, member 1 (BPIFA1) is a secretory protein found in human upper aerodigestive tract mucosa. This innate material is secreted in mucosal fluid or found in submucosal tissue in the human soft palate, lung, uvula, and nasal cavity. BPIFA1 is a critical component of the innate immune response that prevents upper airway diseases.

Synonyms :
BPI fold-containing family A member 1; Lung-specific protein X; PLUNC1; SPLUNC1; Von Ebner protein Hl;

References & Citations :
Tsou YA, Tung MC, Alexander KA, Chang WD, Tsai MH, Chen HL, Chen CM. The Role of BPIFA1 in Upper Airway Microbial Infections and Correlated Diseases. Biomed Res Int. 2018 Sep 3;2018:2021890. doi: 10.1155/2018/2021890. PMID: 30255091; PMCID: PMC6140130.

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