Product Name: Lapatinib
Subtitle: EGFR/HER2 inhibitor,potent,selective and reversible
Biological Activity: Biological Activity of LapatinibDescription Lapatinib is a potent inhibitor of EGFR and ErbB2 with IC50 of 10.8 and 9.2 nM, respectively. Targets EGFR ErbB2 IC50 10.8 nM 9.2 nM
SMLES: CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
CAS NO: 53123-88-9
Standard In CHIKey: BCFGMOOMADDAQU-UHFFFAOYSA-NEndocrinology inhibitors
Standard InChI: InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)
Typrof Compound:
Appearance:
Formula: C29H26ClFN4O4S
M.Wt: 581.06
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/3/841
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine