Name : Human SMR3B Protein
Product Source :
Recombinant Human SMR3B Protein is expressed from HEK293 with mFc (IgG1) tag at the C-terminus. It contains Gln23-Pro79.[Accession | NP_006676.1]
Molecular Weight :
The protein has a predicted MW of 31.47 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human SMR3B on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human SMR3B is greater than 95% as determined by SEC-HPLC.
Background :
SMR3B (P-B, PRL3, PROL3), namely submaxillary gland androgen regulated protein 3B, is a proline-rich protein specifically expressed in salivary glands. The SMR3B is an 8.188 kilodalton protein that belongs to the gene family whose other members are SMR3A and PROL1, which all produce opiorphin homologs. It is predicted to enable endopeptidase inhibitor activity and be involved in cellular response to lipopolysaccharide. SMR3B also regulates pain perception.
Synonyms :
PBII; PRL3; PROL3; P-B
References & Citations :
[1] Saitou M, Gaylord EA, Xu E, May AJ, Neznanova L, Nathan S, Grawe A, Chang J, Ryan W, Ruhl S, Knox SM, Gokcumen O. Functional Specialization of Human Salivary Glands and Origins of Proteins Intrinsic to Human Saliva. Cell Rep. 2020 Nov 17;33(7):108402.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
Fas/CD95 ProteinSynonyms
SOD1 Proteinmedchemexpress
Popular categories:
Others
Ubiquitin-Specific Protease 12