Name : Cynomolgus TPSAB1 protein
Product Source :
Recombinant Cynomolgus TPSAB1 protein is expressed from E.coli with His tag at the N-Terminus. It contains Ile38-Pro282.[Accession | XP_005590891.2]
Molecular Weight :
The protein has a predicted MW of 28.57kDa. The protein migrates to 30-33kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Supplied as 0.22μm filtered solution in 20mM Tris, 250mM NaCl, 2mM CaCl2, 10% Glycerol (pH 8.0).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Cynomolgus TPSAB1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.
Synonyms :
Tryptase alpha/beta-1; Tryptase-1; Tryptase I; Tryptase alpha-1; TPS1; TPS2; TPSB1
References & Citations :
(1) Jackson NE, Wang HW, Bryant KJ, McNeil HP, Husain A, Liu K, Tedla N, Thomas PS, King GC, Hettiaratchi A, Cairns J, Hunt JE. Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation. J Biol Chem. 2008 Dec 5;283(49):34178-87.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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