Product Name: SB202190 (FHPI)
Subtitle: P38 MAPK inhibitor
Biological Activity: Biological Activity of SB202190 (FHPI)A highly selective, potent and cell-permeable inhibitor of p38 MAP kinase. Binds within the ATP pocket of the active kinase (Kd = 38 nM, as measured in recombinant human p38), and selectively inhibits the p38α a
SMLES: C1=CC(=O)C=CC1=C2NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F
CAS NO: 859212-16-1
Standard In CHIKey: NJNKPVPFGLGHPA-UHFFFAOYSA-NToxins_for_Antibody-drug_conjugates_research_Library inhibitors
Standard InChI: InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,23-24H
Typrof Compound:
Appearance:
Formula: C20H14N3OF
M.Wt: 331.34
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/1/140
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol