Product Name: SL-327
Subtitle: Selective MEK1/2 inhibitor
Biological Activity: Biological Activity of SL-327Selective inhibitor of MEK1 and MEK2 (IC50 values are 0.18 and 0.22 μM respectively); blocks hippocampal LTP in vitro. Brain penetrant in vivo, blocking fear conditioning and learning in rats, and producing neuroprotection
SMLES: C1=CC=C(C(=C1)C(=C(N)SC2=CC=C(C=C2)N)C#N)C(F)(F)F
CAS NO: 204697-65-4
Standard In CHIKey: Protease_Inhibitor_Cocktail inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C16H12F3N3S
M.Wt: 335.35
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/1/161
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in ethanol and to 100 mM in DMSO
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: α-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile