Name : Human Tubby Protein
Product Source :
Recombinant Human Tubby Protein is expressed from E.coli with His tag at the N-Terminus. It contains Met1-Glu506.[Accession | P50607-1]
Molecular Weight :
The protein has a predicted MW of 56.74 kDa same as Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Supplied as 0.22μm filtered solution in 20mM Tris, 300mM NaCl, 10% Glycerol, 1mM DTT (pH 7.4).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human Tubby on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
Tubby is the founding member of the tubby-like family of proteins. Tubby-like proteins (TLPs) possess a highly conserved closed β barrel tubby domain at C-terminal and N-terminal F-box.Tubby plays a critical role in trafficking select GPCRs to the cilia.
Synonyms :
TUB; RD5; RDOB
References & Citations :
(1) Sun X, Haley J, Bulgakov OV, Cai X, McGinnis J, Li T. Tubby is required for trafficking G protein-coupled receptors to neuronal cilia. Cilia. 2012 Nov 1;1(1):21. doi: 10.1186/2046-2530-1-21. PMID: 23351594; PMCID: PMC3599646.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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