Name : Mouse BTN2A2 Protein
Product Source :
Recombinant Mouse BTN2A2 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Gln30-Ser244.[Accession | A4QPC6-1]
Molecular Weight :
The protein has a predicted MW of 25.78 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse BTN2A2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Mouse BTN2A2 is greater than 95% as determined by SEC-HPLC.
Background :
Butyrophilin (BTN) genes encode a set of related proteins. Cell surface BTN2A2 protein, such as the B7 family molecule programmed death ligand 1, was upregulated upon activation of T cells.BTN2A2 is a co-inhibitory molecule that modulates T cell-mediated immunity.
Synonyms :
BTN2A2; BT2.2; BTF2; BTN2.2
References & Citations :
(1) Smith IA, Knezevic BR, Ammann JU, Rhodes DA, Aw D, Palmer DB, Mather IH, Trowsdale J. BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation. J Immunol. 2010 Apr 1;184(7):3514-25. doi: 10.4049/jimmunol.0900416. Epub 2010 Mar 5. PMID: 20208008.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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