Name : Human VSIG8 Protein
Product Source :
Recombinant Human VSIG8 Protein is expressed from HEK293 with Fc tag at the C-Terminus. It contains Val22-Gly263.[Accession | P0DPA2]
Molecular Weight :
The protein has a predicted MW of 53.8 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human VSIG8 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human VSIG8 is greater than 95% as determined by SEC-HPLC.
Background :
VSIG8 (V-Set And Immunoglobulin Domain Containing 8) is a Protein Coding gene. Diseases associated with VSIG8 include Retinitis Pigmentosa 30 and Monilethrix. An important paralog of this gene is CXADR.The present work helps characterize the component V-set and immunoglobulin domain containing 8 (VSIG8) in hair shaft and nail plate to assist in understanding its possible relation to disease states.
Synonyms :
VSIG8; C1orf204
References & Citations :
(1) Rice RH, Phillips MA, Sundberg JP. Localization of hair shaft protein VSIG8 in the hair follicle, nail unit, and oral cavity. J Invest Dermatol. 2011 Sep;131(9):1936-8. doi: 10.1038/jid.2011.133. Epub 2011 May 26. PMID: 21614015; PMCID: PMC3156960.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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