Name : Mouse XPNPEP2 Protein
Product Source :
Recombinant Mouse XPNPEP2 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Pro23-Ala650.[Accession | B1AVD1]
Molecular Weight :
The protein has a predicted MW of 72.24 kDa. Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse XPNPEP2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Mouse XPNPEP2 is greater than 95% as determined by SEC-HPLC. Bioactivity Data Measured by its ability to cleave the fluorogenic peptide substrate, H-Lys(2-Aminobenzoyl)-Pro-Pro-p-Nitroanilide (K(Abz)PP-pNA). The specific activity is > 175 pmol/min/µg.
Background :
Aminopeptidase P2 (XPNPEP2) is a receptor for TMTP1 tumor-homing peptide. However, the biological and clinical significance of Aminopeptidase P2 in human cancers remains unknown.
Synonyms :
Xpnpep2 ; Xaa-Pro aminopeptidase 2; Aminoacylproline aminopeptidase; X-Pro aminopeptidase 2
References & Citations :
Li F, Dai Y, Xu H, Huang K, Zhou Y, Luo D, Ma D, Xi L, Lv M, Ma X. XPNPEP2 is associated with lymph node metastasis in prostate cancer patients. Sci Rep. 2019 Jul 11;9(1):10078. doi: 10.1038/s41598-019-45245-5. PMID: 31296901; PMCID: PMC6624198.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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