Name : Human Complement C5a Protein
Product Source :
Recombinant Human C5a Protein is expressed from E.coli with His tag at the N-Terminus. It contains Thr678-Arg751.[Accession | P01031]
Molecular Weight :
The protein has a predicted MW of 9.37 kDa. The protein migrates to 13-14 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Supplied as 0.22μm filtered solution in 20mM PB, 500mM NaCl, 10% Glycerol (pH 7.4).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human C5a on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
The anaphylatoxin C5a is an extremely potent proinflammatory peptide produced during activation of the complement system. The structure of C5a includes a core region (N-terminal residues 1-63) consisting of four, antiparallel alpha-helices held together by three disulfide linkages and a structured C-terminal tail (residues 64-74).
Synonyms :
C5a; CPAMD4; ECLZB
References & Citations :
Pellas TC, Wennogle LP. C5a receptor antagonists. Curr Pharm Des. 1999 Oct;5(10):737-55. PMID: 10526086.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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