Name : Human CD300LG/Nepmucin Protein
Product Source :
Recombinant Human CD300LG/Nepmucin Protein is expressed from HEK293 with His tag at the C-terminus. It contains Leu19-Arg247.[Accession | AAH25395]
Molecular Weight :
The protein has a predicted MW of 26.35 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human CD300LG on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human CD300LG is greater than 95% as determined by SEC-HPLC.
Background :
CD300LG is a novel O-glycosylated member of the CD300 antigen-like family. Besides a classical mucin-like domain, it contains a V-type Ig domain. CD300LG binds lymphocyte L-selectin via its Ig domain and supports lymphocyte rolling via its mucin-like domain. The unique structure and function of CD300LG suggest it may play an important role in inflammation.
Synonyms :
CD300LG; Nepmucin; CLM-9; TREM-4; CD300g; CLM9; TREM4
References & Citations :
Jiang X, Wang H, Li Z, Wei D, Yang Y, Zheng X, Bi J, Zhang C. A monoclonal antibody against a novel Sialomucin CD300LG. Monoclon Antib Immunodiagn Immunother. 2013 Apr;32(2):91-7. doi: 10.1089/mab.2012.0100. PMID: 23607343.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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