Name : Human CD36/SR-B3 Protein
Product Source :
Recombinant Human CD36/SR-B3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Gly30-Asn439.[Accession | P16671-1]
Molecular Weight :
The protein has a predicted MW of 49.5 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human CD36 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human CD36 is greater than 95% as determined by SEC-HPLC.
Background :
CD36, alternatively known as platelet membrane glycoprotein IV (GPIV), GPIIIb, thrombospondin receptor, collagen receptor, fatty acid translocase (FAT), and scavenger receptor class B, member 3 (SR-B3), is an integral membrane glycoprotein that has multiple physiological functions.CD36 is a multifunctional glycoprotein that acts as receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-density lipoprotein (oxLDL), anionic phospholipids, long-chain fatty acids and bacterial diacylated lipopeptides.
Synonyms :
CD36; FAT; FATCHDS7; GPIIIb; GPIV; PAS IV; PAS-4; SCARB3; SRB3; SR-B3; BDPLT10; CHDS7; GP3B
References & Citations :
(1)Cho, Sunghee. CD36 as a Therapeutic Target for Endothelial Dysfunction in Stroke[J]. Current Pharmaceutical Design, 2012, 18(25):3721-3730.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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