Product Name: TAK-632
Subtitle: Pan-RAF inhibitor,potent and selective
Biological Activity: Biological Activity of TAK-632Description TAK-632 is a potent inhibitor of Raf with IC50 of 8.3 nM and 1.4 nM for B-Raf(wt) and C-Raf, respectively. Targets B-Raf C-Raf IC50 8.3 nM 1.4 nM
SMLES: C1CC1C(=O)NC2=NC3=C(S2)C(=C(C=C3)OC4=CC(=C(C=C4)F)NC(=O)CC5=CC(=CC=C5)C(F)(F)F)C#N
CAS NO: 871700-17-3
Standard In CHIKey: IAP inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C27H18F4N4O3S
M.Wt: 554.52
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/1/401
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: N-[7-cyano-6-[4-fluoro-3-[[2-[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide