Name : Mouse CD59a Protein
Product Source :
Recombinant Mouse CD59a Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Leu24-Ser96.[Accession | O55186 ]
Molecular Weight :
The protein has a predicted MW of 35.17 kDa. Due to glycosylation, the protein migrates to 43-53 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Mouse CD59a on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Mouse CD59a is greater than 95% as determined by SEC-HPLC.
Background :
a CD59a fusion protein bound specifically to mouse B cells, and enhanced B cell proliferation in a MLR, demonstrating that B cells express an as yet unidentified ligand for CD59a that aids in B cell activation.
Synonyms :
CD59A glycoprotein;CD59a antigen; MAC-inhibitory; MAC-IP; MACIP; Membrane attack complex inhibition factor; MACIF; Protectin; CD_antigen: CD59
References & Citations :
Sivasankar B, Donev RM, Longhi MP, Hughes TR, Davies R, Cole DS, Morgan BP, Marchbank KJ. CD59a deficient mice display reduced B cell activity and antibody production in response to T-dependent antigens. Mol Immunol. 2007 Apr;44(11):2978-87. doi: 10.1016/j.molimm.2006.12.025. Epub 2007 Feb 12. PMID: 17296227.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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