Product Name: B-Raf inhibitor 1 dihydrochloride
Subtitle: B-Raf inhibitor,potent and selective
Biological Activity: Biological Activity of B-Raf inhibitor 1 dihydrochlorideDescription B-Raf inhibitor 1 dihydrochloride is a potent and selective inhibitor of B-Raf with IC50 values of 0.31 μM and 2 nM for A375 proliferation and A375 p-ERK, respectively. Targets A3
SMLES: CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC=C(C=C3)Cl)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6.Cl.Cl
CAS NO: 923604-59-5
Standard In CHIKey: DNA Alkylator_Crosslinker inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C26H21Cl3N8
M.Wt: 551.86
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/2/484
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: 1-N-(4-chlorophenyl)-6-methyl-5-N-[3-(7H-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine;dihydrochloride