Product Name: DEL-22379
Subtitle: inhibitor of the dimerization of ERK
Biological Activity: Biological Activity of DEL-22379ERK dimerization inhibitor (IC50 ~ 0.5 μM); inhibits ERK dimerization without effecting phosphorylation or kinase activity. Suppresses growth of tumor cells expressing RAS-ERK oncogenes in vitro. Induces apoptosis and
SMLES: O=C1NC2=CC=C(NC(CCN3CCCCC3)=O)C=C2C1=CC4=CNC5=CC=C(OC)C=C54
CAS NO: 843663-66-1
Standard In CHIKey: Integrin inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C26H28N4O3
M.Wt: 444.53
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/2/697
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: N-[2,3-Dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide