Product Name: MK-8245
Subtitle: SCD inhibitor,potent and liver-selective
Biological Activity: Biological Activity of MK-8245Description MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 values of 1 nM, 3 nM and 3 nM for human, rat and mouse SCD1. Targets SCD1 (human) SCD1 (rat) SCD1 (mouse) IC50
SMLES: C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O
CAS NO: 1346704-33-3
Standard In CHIKey: Chloride Channel inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C17H16BrFN6O4
M.Wt: 467.25
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/3/986
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 2-[5-[3-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]-1,2-oxazol-5-yl]tetrazol-2-yl]acetic acid