Product Name: 10Panx
Subtitle: Panx-1 mimetic inhibitor
Biological Activity: Biological Activity of 10PanxPanx-1 mimetic inhibitory peptide that blocks pannexin-1 gap junctions. Inhibits P2X7-mediated dye uptake, ATP-mediated IL-1β release and caspase-1 activation without altering membrane current in macrophages in vitro. Als
SMLES: CC(C)C(C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC3=CNC4=CC=CC=C43)N
CAS NO: 33069-62-4
Standard In CHIKey: Neurological Disease inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C58H79N15O16
M.Wt: 1242.37
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/256/3/917
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 1 mg/ml in 20mM PBS buffer with gentle warming
Storage: Store at -20℃
Purity: >98%
Chemical Name: