Product Name: NVP-BGT226
Subtitle: PI3K/mTOR inhibitor,selective and novel
Biological Activity: Biological Activity of NVP-BGT226Description BGT226 (NVP-BGT226) is a novel inhibitor of class I PI3K/mTOR with IC50 values of 4 nM, 63 nM and 38 nM for PI3Kα, PI3Kβ and PI3Kγ, respectively. Targets PI3Kα PI3Kγ PI3Kβ IC50 4 nM 38 nM
SMLES: CN1C2=CN=C3C=CC(=CC3=C2N(C1=O)C4=CC(=C(C=C4)N5CCNCC5)C(F)(F)F)C6=CN=C(C=C6)OC.C(=CC(=O)O)C(=O)O
CAS NO: 1345808-25-4
Standard In CHIKey: Histone Methyltransferase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C28H25F3N6O2.C4H4O4
M.Wt: 650.6
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/861
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: (Z)-but-2-enedioic acid;8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]imidazo[4,5-c]quinolin-2-one