Product Name: ETP-46464
Subtitle: ATR inhibitor,potent and selective
Biological Activity: Biological Activity of ETP-46464Description ETP-46464 is a potent and selective inhibitor of ATR with an IC50 value of 25 nM. Targets mTOR ATR DNA-PK PI3Kα ATM IC50 0.6 nM 14 nM 36 nM 170 nM 545 nM
SMLES: CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3COC2=O)C5=CC6=CC=CC=C6N=C5
CAS NO: 1044870-39-4
Standard In CHIKey: Angiotensin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C30H22N4O2
M.Wt: 470.52
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/3/1025
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 2-methyl-2-[4-(2-oxo-9-quinolin-3-yl-4H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl]propanenitrile