Product Name: RO4929097
Subtitle: γ secretase inhibitor
Biological Activity: Biological Activity of RO4929097Description RO4929097 is an inhibitor of γ secretase with IC50 of 4 nM, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Targets γ secretase Aβ40 ICN IC50 4 nM
SMLES: CC(C)(C(=O)NCC(C(F)(F)F)(F)F)C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3NC1=O
CAS NO: 62996-74-1
Standard In CHIKey: Parasite inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H20F5N3O3
M.Wt: 469.4
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/258/1/339
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 2,2-dimethyl-N-[(7S)-6-oxo-5,7-dihydrobenzo[d][1]benzazepin-7-yl]-N-(2,2,3,3,3-pentafluoropropyl)propanediamide