Product Name: VX-222 (VCH-222, Lomibuvir)
Subtitle: NNI of HCV RNA polymerase
Biological Activity: Biological Activity of VX-222 (VCH-222, Lomibuvir)Description VX-222 is a potent and selective inhibitor of HCV RNA-dependent RNA polymerase with IC50 value of 0.94-1.2 μM. Targets HCV RNA-dependent RNA polymerase IC50 0.94-1.2 μM
SMLES: CC1CCC(CC1)C(=O)N(C2CCC(CC2)O)C3=C(SC(=C3)C#CC(C)(C)C)C(=O)O
CAS NO: 1009820-21-6
Standard In CHIKey: Apoptosis inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C25H35NO4S
M.Wt: 445.6
General Tips: for obtaining a higher concentration: Please warm the tube at 37℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/258/1/58
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 5-(3,3-dimethylbut-1-ynyl)-3-[(4-hydroxycyclohexyl)-(4-methylcyclohexanecarbonyl)amino]thiophene-2-carboxylic acid