Product Name: OSI-930
Subtitle: Inhibitor of Kit, KDR, Flt, CSF-1R, c-Raf and Lck
Biological Activity: Biological Activity of OSI-930Description OSI-930 is a potent inhibitor of receptor tyrosine kinases with IC50 values of 80 nM, 9 nM, 8 nM, 15 nM, 41 nM and 22 nM for c-Kit, KDR, Flt, CSF-1R, c-Raf and Lck , respectively. Targets c-Kit KDR Flt C
SMLES: C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F
CAS NO: 453562-69-1
Standard In CHIKey: Mixed Lineage Kinase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H16F3N3O2S
M.Wt: 443.44
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/1/286
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 3-[(4-Quinolinylmethyl)amino]-N-[4-(trifluoromethoxy)phenyl]-2-thiophenecarboxamide