Product Name: AY 9944 dihydrochloride
Subtitle: Hedgehog Inhibitor
Biological Activity: Biological Activity of AY 9944 dihydrochlorideInhibitor of hedgehog (Hh) signaling, possibly via several mechanisms. Inhibits Δ7-dehydrocholesterol reductase (IC50 = 13 nM), thus reduces cholesterol biosynthesis, and also inhibits cholesterol esteri
SMLES:
CAS NO: 171500-79-1
Standard In CHIKey: NRVIEWRSGDDWHP-UHFFFAOYSA-NBeta-secretase inhibitors
Standard InChI: InChI=1S/C22H28Cl2N2.2ClH/c23-21-7-3-1-5-19(21)15-25-13-17-9-11-18(12-10-17)14-26-16-20-6-2-4-8-22(20)24;;/h1-8,17-18,25-26H,9-16H2;2*1H
Typrof Compound:
Appearance:
Formula: C22H28Cl2N2.2HCl
M.Wt: 464.3
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/2/925
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in water
Storage: Desiccate at RT
Purity: >98%
Chemical Name: trans-N,N-bis[2-Chlorophenylmethyl]-1,4-cyclohexanedimethanamine dihydrochloride