Product Name: PD 161570
Subtitle:
Biological Activity: Biological Activity of PD 161570Selective FGFR inhibitor (IC50 values are 40, 262 and 3700 nM for FGFR, PDGFR and EGFR respectively). Inhibits FGFR receptor phosphorylation (IC50 = 622 nM) and growth of A121 cells in vitro.
SMLES: ClC1=[C@@](C(Cl)=CC=C1)[C@@]2=CC3=CN=C(N=C3N=C2NC(NC(C)(C)C)=O)NCCCCN(CC)CC
CAS NO: 28822-58-4
Standard In CHIKey: PI3K_Akt_mTOR inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C26H35Cl2N7O
M.Wt: 532.51
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/2/965
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage: Store at -20℃
Purity: >98%
Chemical Name: N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N-(1,1-dimethylethyl)urea