Product Name: KRCA 0008
Subtitle:
Biological Activity: Biological Activity of KRCA 0008Potent Ack1 and anaplastic lymphoma kinase (ALK) dual inhibitor (IC50 values are 4 and 12 nM respectively). Inhibits lung cancer H3122 cell proliferation (IC50 = 80 nM). Attenuates H3122 cell xenograft tumor growth in mice.
SMLES: N/A
CAS NO: 1032754-81-6
Standard In CHIKey: GSK-3 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C30H37ClN8O4
M.Wt: 609.12
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/2/978
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO and to 100 mM in ethanol
Storage: Store at -20℃
Purity: >98%
Chemical Name: 1,1'-[(5-Chloro-2,4-pyrimidinediyl)bis[imino(3-methoxy-4,1-phenylene)-4,1-piperazinediyl]]bisethanone